Georg Büldt, Forschungszentrum Jülich, Institute for Structural Biology and Biophysics (ISB), Molecular Biophysics and Heinrich-Heine-Universität Düsseldorf

Study of energy-converting and signaling proteins: Bacteriorhodopsin halorhodopsin, cytochrome c oxidase. Sensory rhodopsin II in complex with its transducer, arrestins, X-ray crystallography, X-ray and neutron small-angle scattering, optical spectroscopy.



Selected Publications

J. Granzin, U. Wilden, H.-W. Choe, J. Labahn, B. Krafft and G. Büldt (1998). X-ray crystal structure of arrestin from bovine rod outer segments. Nature 391, 918-921.

H.J. Sass, G. Büldt, R. Gessenich, D. Hehn, D. Neff, R. Schlesinger, J. Berendzen and P. Ormos (2000). Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin. Nature 406, 649-653.

V.I. Gordeliy, J. Labahn, R. Efremov, R. Moukhametzianov, J. Granzin, R. Schlesinger, G. Büldt, T. Savopol, A.J. Scheidig, J. P. Klare, and J. M. Engelhard (2002). Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex. Nature 419, 484-487.

J. Labahn, S. Neumann, G. Büldt, M.-R. Kula, J. Granzin (2002). An alternative mechanism for amidase signature enzymes. J. Mol. Biol. 322, 1053-1064.

R. Moukhametzianov, J.P. Klare, R. Efremov, C. Baeken, A. Göppner, J. Labahn, M. Engelhard, G. Büldt and V.G. Gordeliy (2006). Development of the signal in sensory rhodopsin and its transfer to the cognate transducer. Nature 440, 115-119.

R. Efremov, V.I. Gordeliy, J. Heberle and G. Büldt (2006).Time-resolved microspectroscopy on a single crystal of bacteriorhodopsin reveals lattice induced differences in the photocycle kinetics. Biophys. J., 91, 1441-1451.

O.S. Mironova, I.L. Budyak, G. Büldt, R. Schlesinger, J. Heberle (2007). FT-IR difference spectroscopy elucidates crucial interactions of sensory rhodopsin I with the cognate transducer HtrI. Biochemistry, 46, 9399-9405.