Andreas Offenhäusser, Institute of Bio- and Nanosystems (IBN-2, Bioelectronics) and RWTH Aachen

Study of functional coupling of sensory cells and neurons with microelectronic devices. Signal processing in biological neuronal networks. Electronic DNA-Chip. Biophysics of lipid bilayers and membrane receptors. Biosensors and bio-magnetic sensors.



Selected Publications

Lingler S, Rubinstein I, Knoll W, Offenhausser A. (1997) Fusion of small unilamellar lipid vesicles to alkanethiol and thiolipid self-assembled monolayers on gold. Langmuir, 13(26):7085-7091

Scholl M, Sprossler C, Denyer M, Krause M, Nakajima K, Maelicke A, Knoll W, Offenhausser A. (2000) Ordered networks of rat hippocampal neurons attached to silicon oxide surfaces. Journal of Neuroscience Methods, 104(1):65-75

Offenhausser A, Knoll W. (2001) Cell-transistor hybrid systems and their potential applications. Trends in Biotechnology, 19(2):62-66

Baumgart T, Offenhauser A. (2002) Lateral diffusion in substrate-supported lipid monolayers as a function of ambient relative humidity. Biophysical Journal, 83(3): 1489-1500

Vogt AK, Lauer L, Knoll W, Offenhausser A. (2003) Micropatterned substrates for the growth of functional neuronal networks of defined geometry. Biotechnology Progress, 19(5): 1562-1568

Uslu F, Ingebrandt S, Mayer D, Bocker-Meffert S, Odenthal M, Offenhausser A. (2004) Labelfree fully electronic nucleic acid detection system based on a field-effect transistor device. Biosensors & Bioelectronics, 19(12): 1723-1731

Vogt AK, Brewer GJ, Decker T, Böcker-Meffert S, Jacobsen V, Kreiter M, Knoll W, Offenhäusser A. (2005) Independence of synaptic specificity from neuritic guidance. Neuroscience, 134(3):783-790

Vogt AK, Wrobel G, Meyer W, Knoll W, Offenhäusser A. (2005) Synaptic plasticity in micropatterned neuronal networks. Biomaterials, 26(15):2549-2557.

Wolfrum B, Mourzina Y, Sommerhage F, Offenhäusser A. (2006) Suspended Nanoporous Membranes as Interfaces for Neuronal Biohybrid Systems Nano Lett, 6(3): 453 -457

B. Wolfrum, Y. Mourzina, D. Mayer, D. Schwaab, A. Offenhausser (2006) Fabrication of large-scale patterned gold-nanopillar arrays on a silicon substrate using imprinted porous alumina templates. Small, 2(11):1256-1260.

S Meyburg, G Wrobel, R Stockmann, J Moers, S Ingebrandt, A Offenhäusser (2006) Single cell recordings with pairs of complementary transistors. Applied Physics Letters, 89, 013901.

A. Reska, P. Gasteier, P. Schulte, A. Offenhäusser, M. Möller, J. Groll (2008) Ultrathin coatings with reactivity change by time enable functional in vitro networks of insect neurons. Advanced Materials, 20, 2751-2755.

G. Wrobel, M. Höller, S. Ingebrandt, S. Dieluweit, F. Sommerhage, HP Bochem, A. Offenhäusser (2008) Transmission electron microscopy study of the cell-sensor interface. J R Soc Interface, 5:213-22.